The Effect of Suspended Moxa Stick Moxibustion on Points Shenshu(BL23) and Guanyuan(CV4) on the Pituitary-adrenal ;Axis and the Pituitary-thyroid Axis in Rats with Kidney Yang Deficiency
10.13460/j.issn.1005-0957.2016.12.1469
- VernacularTitle:艾条悬灸肾俞、关元对肾阳虚大鼠垂体-肾上腺轴和垂体-甲状腺轴的影响
- Author:
Youjiang MIN
;
Haihua YAO
;
Lihong CHENG
- Keywords:
Moxa stick moxibustion;
Kidney yang deficiency;
Pituitary-adrenal axis;
Pituitary-thyroid axis;
Rats
- From:
Shanghai Journal of Acupuncture and Moxibustion
2016;35(12):1469-1472
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of suspended moxa stick moxibustion on points Shenshu(BL23) and Guanyuan(CV4) on the pituitary-adrenal axis and the pituitary-thyroid axis in rats with kidney yang deficiency. Method A rat model of corticosterone kidney yang deficiency was made by intramuscular injection of hydrocortisone. The rats were randomized into model control and moxibustion treatment groups. A blank control group was set up. The moxibustion treatment group received suspended moxa stick moxibustion on points Shenshu and Guanyuan 20 min once daily, for a total of 14 times. After the completion of treatment, serum CORT, ACTH, T3, T4 and TSH contents were measured by ELISA and pituitary expressions of ACTH and TSH mRNA were determined by RT-PCR. Result There was no significant difference in serum CORT (P>0.05), there were significant differences in serum ACTH, T4 and TSH and pituitary ACTH and TSH mRNA (P<0.05) and there was a very significant difference in serum T3 (P<0.01) between the moxibustion treatment and model control groups. There were no significant differences in the above indicators between the moxibustion treatment and blank control groups (P>0.05). Conclusion Suspended moxa stick moxibustion on points Shenshu and Guanyuan produces a therapeutic effect on rat kidney yang deficiency by decreasing serum TSH content, down-regulating pituitary TSH mRNA expression, increasing serum ACTH, T3 and T4 contents and up-regulating pituitary ACTH mRNA expression.
