Diagnostic value of puncture feeling combined with fine-needle aspiration cytology for thyroid nodules

VernacularTitle:甲状腺细针穿刺手感联合细胞学检查对甲状腺结节良恶性的研究
Author: Jieli LUO ; Jianshe CHEN ; Yang SUN ; Pintong HUANG
Keywords: Ultrasonography; Thyroid nodules; Biopsy,fine-needle; Puncture feeling
From:Chinese Journal of Ultrasonography 2016;25(11):966-969
CountryChina
Language:Chinese
Abstract: Objective To evaluate the diagnostic value of puncture feeling combined with fine-needle aspiration cytology (FNAC) for thyroid nodules.Methods One thousand and fourteen thyroid nodules were retrospectively analyzed.Eighty-six thyroid nodules were performed repeat FNAC.All nodules were confirmed by pathology,the agreement of puncture feeling at different time was evaluated by Kappa test.Results There were 751 malignant nodules and 263 benign nodules.Sensitivity and accuracy of FNAC combined with puncture feeling were higher than those of single FNAC or single puncture feeling (x2 =11.609,4.433 and P =0.00,0.04;x2 =19.369,6.697 and P =0.00,0.01,respectively).There were no statistically differences in the sensitively and accuracy between single FNAC and puncture feeling (x2 =1.230,0.242 and P =0.27,0.62,respetively).The Kappa values of inter-observer and intra-observer were 0.829(P =0.00) and 0.885(P =0.00) respectively with statistically significance.Conclusions Puncture feeling combined with FNAC can improve the sensitivity and accuracy in the diagnosis of thyroid nodules,the reproducibility of puncture feeling is excellent.