Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene.
10.4174/jkss.2012.82.3.185
- Author:
Jun Won MIN
1
;
Youn Joon PARK
;
Hee Jin KIM
;
Myung Chul CHANG
Author Information
1. Department of Surgery, Dankook University College of Medicine, Cheonan, Korea. changmc@dankook.ac.kr
- Publication Type:Case Report
- Keywords:
Pheochromocytoma;
RET;
Germ-line mutation
- MeSH:
Adult;
Germ-Line Mutation;
Humans;
Oncogenes;
Pheochromocytoma;
Thyroid Neoplasms
- From:Journal of the Korean Surgical Society
2012;82(3):185-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic test detected a L790F germline mutation of RET oncogene. The author found a necessity for genetic tests in cases of young-age, bilateral pheochromocytoma.
