Advances of molecular mechanisms of oxidative stress in obstructive sleep apnea syndrome and stroke
10.3760/cma.j.issn.1008-6706.2017.03.037
- VernacularTitle:阻塞性睡眠呼吸暂停综合征氧化应激反应的分子机制与脑卒中的关联性研究进展
- Author:
Honghao MAN
;
Shuqiang YAO
;
Yongpeng YU
;
Yuhua BI
;
Chunyu DONG
;
Xiaohong QIAO
;
Weiping JU
- Keywords:
Sleep apnea,obstructive;
Oxidative stress;
Stroke
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(3):462-465
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA)is a high incidence of potentially dangerous disease,characterized by intermittent hypoxia or hypercapnia.It is an independent risk factor for ischemic stroke.Currently a number of studies have confirmed OSA closely associated with oxidative stress.In this paper,the complex mechanisms of oxidative stress in the OSA and the occurrence of stroke will be reviewed,such as promoting atherosclerosis,damaging the mitochondria,ischemia -reperfusion injury,ischemic preconditioning.To investigate the relationship between OSA,oxidative stress and stroke from molecular mechanisms.
