Micro-sphere culture gathers cancer stem cell and its potential clinical application
10.3969/j.issn.1000-8179.2017.03.944
- VernacularTitle:微球体培养富集肿瘤干细胞及其潜在的临床应用
- Author:
Xin FU
;
Ke WANG
- Keywords:
cancer stem cell;
micro-sphere culture;
biomarker;
microsystem
- From:
Chinese Journal of Clinical Oncology
2017;44(3):136-141
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cell hypothesis has become a new theory. According to this theory, cancer stem cells play a decisive role in car-cinogenesis, progression, and metastasis. This theory offered new ideas and strategies for cancer treatment. However, only a small fraction of cells in a tumor were cancer stem cells. Therefore, the identification and enrichment of these cells are significant challenges for numerous researchers conducting further study. Micro-sphere culture has been an effective tumor stem cell enrichment technolo-gy in recent years. The application of this technique makes the cancer stem cell research process easy. In addition, it makes the evalua-tion of tumor progression and prognosis of patients in clinical possible. This article will focus on the applications of this technology, and microsystem integration will be described in detail.
