Medical countermeasures against chemical threats:a review of antidotes
10.3867/j.issn.1000-3002.2016.12.019
- VernacularTitle:化学威胁的医学对抗：抗毒药物研究现状和进展
- Author:
Wenxia ZHOU
;
Gang LIU
;
Yongxiang ZHANG
- Keywords:
chemical threats;
antidotes;
nerve agent;
sulfur mustard;
cyanide
- From:
Chinese Journal of Pharmacology and Toxicology
2016;30(12):1411-1418
- CountryChina
- Language:Chinese
-
Abstract:
Chemical warfare agents and chemical terrorism agents have been identified as one of the major threats to human survival and national security currently. The key to dealing with these threats is the effective medical countermeasures of which specific antidotes take center stage. In the past decade,real or potential chemical threats which has sparked regional conflicts,terrorist activities or chemical accidents intentionally or unintentionally have increased the investment in antidotes research and development worldwide. Here,we introduced the research status on medical countermeasures against chemical threat by giving an overview of the United States ″Countermeasures Against Chemi?cal Threats(CounterACT)Program″,and then the recent research progress in antidotes against nerve agents,sulfur mustard and cyanide toxicities were reviewed.
