New progress in study of inflammatory reflex
10.3969/j.issn.1000-4718.2016.12.031
- VernacularTitle:炎症反射研究新进展
- Author:
Yun GU
;
Zhong ZHUANG
- Keywords:
Inflammatory reflex;
Inflammation;
Vagus nerve;
Cholinergic neurons;
Sympathetic nerve
- From:
Chinese Journal of Pathophysiology
2016;32(12):2300-2304
- CountryChina
- Language:Chinese
-
Abstract:
Proinflammatory cytokines induced by peripheral immune challenge can activate the inflammatory reflex, which results in negative-feedback control of inflammation .Some recent studies revealed that it is the splanchnic nerve , not the vagus nerve , to constitute the efferent arm of the inflammatory reflex .Further researches are needed to iden-tify the neural construction and regulatory mechanism of the inflammatory reflex , which might be harnessed for the treatment of inflammation and the development of anti-inflammatory drugs .