Short-term clinical evaluation of different pharmaceutical forms of triamcinolone acetonide in the treatment of oral lichen planus of erosive type
10.3969/j.issn.1001-3733.2016.06.021
- VernacularTitle:不同剂型曲安奈德治疗糜烂型口腔扁平苔藓的短期疗效评价
- Author:
Ying ZHANG
;
Dan CUI
- Keywords:
Triamcinolone acetonide(TA);
Erosive;
Oral lichen planus(OLP)
- From:
Journal of Practical Stomatology
2016;32(6):844-847
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of different forms of triamcinolone acetonide( TA) in the treatment of buccal erosive oral lichen planus (EOLP). Methods:120 EOLP patients were randomly divided into 4 groups(n=30) and treated with Kangfuxin mouth-wash followed by topical ointment of( TA) , TA injection, TA mouth-wash and only Kangfuxin mouth-wash only, respectively. Before treatment, 1, 2 and 4 weeks after treatment, the pain (VAS score) and erosion area were measured, the effects were compared among groups. Results:The VAS scores of A, B and C groups were significantly lower than those of the control group after 1, 2 and 4 week treatment, and the total effective rate was significantly higher than that of the control group, respectively(P<0. 05). The VAS score was lower and total effective rate was higher in group A and group B than those in group C(P<0. 05), but there was no statistically sig-nificant difference between group A and B(P>0. 05). The average erosion area of group A and B was significantly smaller than that of the control group after 1, 2 and 4 week treatment(P<0. 05). There was no significant difference between group C and the control group after 1 and 2 week treatment(P>0. 05), but 4 weeks after treatment, the average area of erosion of group C was significantly smaller than that of the control group(P<0. 05). Conclusion:Triamcinolone acetonide is effective in the treatment of OLP and the oral oint-ment form is safe and convenient for OLP treatment.
