Cost-effectiveness Analysis of Xiyanping Injection and Ribavirin Injection for Common Type Hand-foot-mouth Disease in Children
10.6039/j.issn.1001-0408.2016.35.02
- VernacularTitle:喜炎平注射液和利巴韦林注射液治疗普通型儿童手足口病的成本-效果分析
- Author:
Ting WANG
;
Fen XIONG
;
Hongmei TANG
;
Yuna CHAI
;
Yusheng HUANG
;
Yuan LIU
;
Rufan ZHONG
- Keywords:
Decision tree model;
Cost-effectiveness analysis;
Xiyanping injection;
Ribavirin injection;
Common type hand-foot-mouth disease;
Children;
Tornado diagram
- From:
China Pharmacy
2016;27(35):4900-4903
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare cost-effectiveness of Xiyanping injection and Ribavirin injection in the treatment of com-mon type hand-foot-mouth disease (HFMD) in children,and to provide evidence for rational drug use in the clinic. METHODS:The literatures about Xiyanping injection in the treatment of common type HFMD in children using Ribavirin injection as control were retrieved from CNKI,VIP,Wanfang,PubMed,Cochrane library and other databases. The decision tree was established with TreeAge Pro 2011 software to conduct cost-effectiveness analysis. Tornado diagram was used to analyze sensitive factors;single fac-tor and double factors sensitivity analysis were also conducted. RESULTS & CONCLUSIONS:The total cost of Xiyanping injection and Ribavirin injection were 2 887.53 and 3 058.72 yuan,respectively. The total effective rates were 92.49% and 78.12%. Xiyan-ping injection shows cost-effectiveness advantage. The results of cost-effectiveness analysis were supported by sensitivity analysis.
