Role of endoplasmic reticulum stress in arsenic toxicity induced damage: a recent advance
10.3760/cma.j.issn.2095-4255.2017.01.016
- VernacularTitle:内质网应激在砷毒性损伤机制中作用的研究进展
- Author:
Weiwei SUN
;
Dianjun SUN
- Keywords:
Arsenic poisoning;
Endoplasmic reticulum stress;
Unfolded protein response
- From:
Chinese Journal of Endemiology
2017;36(1):66-69
- CountryChina
- Language:Chinese
-
Abstract:
Arsenic exposure can cause health problems to our body but arsenic can also be used to treat some diseases through induction of cell apoptosis.These effects are due to arsenic toxicity,but the mechanism is still unclear.Recent studies have showed that cell apoptosis induced by endoplasmic reticulum stress is associated with the mechanism.Therefore,in this paper,the role of endoplasmic reticulum stress in arsenic toxicity has been reviewed and some problems in current studies are pointed out,so as to provide clues and basis for further scientific research.
