To evaluate hepato-cellular lesions status in drug allergic patient treated in Clinical Immuno-Allergy Department, Bach Mai hospital 2000-2003
- Author:
Nguyen Thi Van
- Publication Type:Journal Article
- Keywords:
drug allergy, hepato-cellular lesions
- MeSH:
Drug Hypersensitivity;
Liver;
Therapeutics
- From:Journal of Vietnamese Medicine
2004;305(12):12-17
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The clinical and laboratory characteristics of 139 drug-allergy patients with hepatic cell failure at Allergy and Immunology Department of Hospital Bach Mai from 1999-2003. The result: clinical manifestation of hepatic injury due to drug are very diversified including jaundice, yellow-eyed, ascites, conscious disorder, haemorrhage of skin and mucous, dyspepsia. The laboratory result showed that patients were reduced synthetic process of albumin and protid of liver, coagulation defects due to reducing rate of prothrombin, increasing significantly enzyms of liver. The reason of hepatic cell failure include: traditional drug, psychiatry drug and Rifampicin. Antibiotic drug and epilepsy drug have the same rate
