The mechanism of Wnt/β-catenin signaling pathway in glioma invasion
10.3760/cma.j.issn.1673-422X.2017.02.016
- VernacularTitle:Wnt/β-catenin信号转导通路影响神经胶质瘤侵袭的机制
- Author:
Jing LIU
;
Xiaogang WANG
;
Geng GUO
;
Yuanli ZHAO
- Keywords:
Glioma;
Neoplasm invasiveness;
MicroRNAs;
Wnt/β-catenin
- From:
Journal of International Oncology
2017;44(2):139-141
- CountryChina
- Language:Chinese
-
Abstract:
Invasion of glioma is a complex process with multiple steps and multiple factors,including the inhibition of tumor cell adhesion,the degradation of extracellular matrix,the promotion of tumor cells migration and angiogenesis.The abnormal activation of Wnt/β-catenin signaling pathway is closely related to the invasion of glioma.The study of Wnt/β-catenin pathway affecting invasion mechanism of glioma will provide new ideas and targets for the treatment of glioma.
