TACE combined with MWA versus simple TACE for the treatment of large hepatic cancers: a meta-analysis of curative effect
10.3969/j.issn.1008-794X.2017.03.009
- VernacularTitle:肝动脉化疗栓塞联合微波消融与单独肝动脉化疗栓塞治疗大肝癌疗效meta分析
- Author:
Qifeng CHEN
;
Zhenyu JIA
;
Zhengqiang YANG
;
Wentao WU
;
Haibin SHI
- Keywords:
transcatheter arterial chemoembolization;
microwave ablation;
large liver cancer;
meta-analysis
- From:
Journal of Interventional Radiology
2017;26(3):225-231
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the curative effect of transcatheter arterial chemoembolization (TACE) combined with microwave ablation (MWA) with that of simple TACE in treating large liver cancers.Methods A computer-based search assisted by manual searching for TACE+MWA vs simple TACE clinical control trials for large liver cancers was conducted.The patient survival,tumor response and complications were enrolled in the scope of analysis.Results A total of 16 papers met the inclusion criteria,which included 1199 patients in total.Meta-analysis indicated that one-,2-and 3-year survival rates of TACE+MWA group were better than those of simple TACE group,and the differences between the two groups were statistically significant (P＜0.01).The complete response (CR) rate and partial response (PR) rate of TACE+MWA group were higher than those of simple TACE group,and the differences between the two groups were statistically significant (P＜0.01).The stable disease (SD) rate and progressive disease (PD) rate of TACE+MWA group were lower than those of simple TACE group,and the differences between the two groups were statistically significant (P＜0.01).Conclusion For the treatment of large liver cancers,TACE +MWA is superior to simple TACE.(J Intervent Radiol,2017,26:225-231)
