A Case of Apert's Syndrome with Encephalocele and Hypogenesis of Corpus Callosum.
- Author:
Min Kyoung KWON
1
;
Ja Yun YUN
;
Mi Ran KIM
;
Kon Hee LEE
;
Hae Ran LEE
;
Kwang Nam KIM
Author Information
1. Department of Pediatirics, College of Medicine, Hallym University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Apert's syndrome;
Encephalocele;
Hypogenesis of corpus callosum
- MeSH:
Central Nervous System;
Cleft Palate;
Corpus Callosum*;
Cranial Fontanelles;
Cranial Sutures;
Dilatation;
Ear;
Encephalocele*;
Fingers;
Foot;
Forehead;
Hand;
Head;
Humans;
Hypertelorism;
Magnetic Resonance Imaging;
Neck;
Nose;
Occipital Bone;
Skin;
Sutures;
Syndactyly;
Third Ventricle;
Toes
- From:Journal of the Korean Pediatric Society
2001;44(7):832-836
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Apert's syndrome(acrocephalosyndactyly) is a rare congenital anomaly that is characterized by the combination of premature fusion of multiple cranial sutures primarily involving the coronal suture and severe symmetrical syndactyly of fingers and toes. Some patients of this syndrome have various abnormalities of the central nervous system. We experienced a case of Apert's syndrome with craniofacial malformations, symmetric syndactyly, occipital encephalocele and hypogenesis of corpus callosum. She had a oxycephalic head with small sized anterior fontanelle, elongated forehead, hypertelorism, down-slanting palpebral fissures, flattened nose, cleft palate, low set ears and short neck. A 5x3 cm sized scalp-covered soft mass protruded in the occipital area through defect of the occipital bone. MRI showed hypogenesis of corpus callosum, occipital encephalocele, dilatation of the lateral and the third ventricles. She also had hands and feet with symmetric syndactyly involved skin and soft tissue but not bones.
