Research advances in risk factors for hepatocellular carcinoma in chronic hepatitis C patients with sustained virologic response
10.3969/j.issn.1001-5256.2017.03.033
- VernacularTitle:获得持续病毒学应答的慢性丙型肝炎患者发生肝细胞癌危险因素的研究进展
- Author:
Luxuan YANG
;
Xin ZHANG
- Keywords:
hepatitis C,chronic;
sustained virologic response;
carcinoma,hepatocellular;
review
- From:
Journal of Clinical Hepatology
2017;33(3):543-547
- CountryChina
- Language:Chinese
-
Abstract:
Nowadays it is generally believed that chronic hepatitis C patients who are treated with interferon combined with ribavirin and achieve sustained virologic response are considered cured,but in clinical practice,some patients develop hepatocellular carcinoma (HCC) after achieving sustained virologic response.This article summarizes and analyzes the studies on chronic hepatitis C patients who developed HCC after achieving sustained virologic response and identifies the risk factors for the development of HCC.It has been proved that some of the risk factors,such as male sex,age,liver cirrhosis,and diabetes,may be related to the development of HCC,but a lot of risk factors still await for further investigation.