Management of Patients with Long QT Syndrome.
10.4070/kcj.2016.46.6.747
- Author:
Yongkeun CHO
1
Author Information
1. Department of Internal Medicine, Kyungpook National Univeristy Hospital, Daegu, Korea. choyk@knu.ac.kr
- Publication Type:Review
- Keywords:
Long QT syndrome;
Adrenergic beta-blocker;
Sympathectomy;
Defibrillators, implantable
- MeSH:
Channelopathies;
Death, Sudden;
Defibrillators, Implantable;
Humans;
Long QT Syndrome*;
Stress, Psychological;
Sympathectomy;
Syncope;
Torsades de Pointes;
Ventricular Fibrillation
- From:Korean Circulation Journal
2016;46(6):747-752
- CountryRepublic of Korea
- Language:English
-
Abstract:
Long QT syndrome (LQTS) is a rare cardiac channelopathy associated with syncope and sudden death due to torsades de pointes and ventricular fibrillation. Syncope and sudden death are frequently associated with physical and emotional stress. Management of patients with LQTS consists of life-style modification, β-blockers, left cardiac sympathetic denervation (LCSD), and implantable cardioverter-defibrillator (ICD) implantation. Prohibition of competitive exercise and avoidance of QT-prolonging drugs are important issues in life-style modification. Although β-blockers are the primary treatment modality for patients with LQTS, these drugs are not completely effective in some patients. Lifelong ICD implantation in young and active patients is associated with significant complications. LCSD is a relatively simple and highly effective surgical procedure. However, LCSD is rarely used.
