Function of Cystatin SN and its relationship with tumors

VernacularTitle:半胱氨酸蛋白酶抑制剂SN的功能及其与肿瘤的关系
Author: Shanshan JIANG ; Yan XIN
Keywords: Cysteine proteinase inhibitors; Neoplasms; Function
From: Journal of International Oncology 2017;44(3):201-204
CountryChina
Language:Chinese
Abstract: Cysteine protease inhibitor SN (Cystatin SN) is a secretory protein encoded by CST1,with the promotion of cell senescence and apoptosis activity,playing an important role in the regulation of proteolytic activity.Many studies have found that Cystatin SN is abnormally expressed in various kinds of tumors,and is closely related with the tumorigenesis and progression.Cystatin SN may play an important role in the diagnosis and prognosis of tumors.