Novel molecular diagnostic markers for liver fibrosis
10.3969/j.issn.1001-5256.2017.03.009
- VernacularTitle:肝纤维化新型分子诊断标志物
- Author:
Jinghua DU
;
Yuemin NAN
- Keywords:
liver cirrhosis;
biological markers;
diagnosis
- From:
Journal of Clinical Hepatology
2017;33(3):445-450
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrosis is an important pathological stage for the progression of chronic liver diseases to liver cirrhosis.Timely and accurate assessment of fibrosis degree plays an important role in guiding the treatment of chronic liver diseases.With the development of molecular biology techniques and wide application of molecular diagnostic techniques,the measurement of novel serum molecular diagnostic markers may contribute to the early diagnosis and precise treatment of liver fibrosis.A number of novel serum molecular markers with a diagnostic value have been identified,including fibroblast factor,matrix metalloproteinases and their inhibitors,extracellular matrix-related markers,and non-coding RNAs.In addition,genomics,proteomics,and metabolomics also have certain diagnostic values.
