The near future and the forward curative effect of Autologous islet transplantation in the treatment of chronic pancreatitis

VernacularTitle:自体胰岛移植治疗慢性胰腺炎的近期及远期疗效
Author: Sheng ZHANG ; Yonghua CHEN ; Siming XIE ; Xubao LIU ; Gang MAI
Keywords: Chronic pancreatitis; Islet autologous transplantation pancreatectomy
From: Chinese Journal of Endocrine Surgery 2016;10(6):513-516
CountryChina
Language:Chinese
Abstract: Chronic pancreatitis (CP) is a kind of disease with the sustainable and irreversible damage of the tissue structure and function of pancreas,which may be caused by alcohol,gene,gallstone,metabolism,deformity and other factors.The clinical manifestations are intractable abdominal pain and disorder of the internal and external secretion of pancreas.At present,the main purpose of the treatment for chronic pancreatitis is to relieve patients' pain,and to maintain the secretion function of pancreas as far as possible.The main surgical procedures for chronic pancreatitis includes the pancreatic resection,nerve block and decompression drainage of the pancreatic duct.In recent years,people hve paid more attenntion to the whole pancreas resection combined autologous transplantation due to retaining some functions of the islet cells.After whole pancreas resection combined autologous transplantation,the abdominal pain will relieve and the life quality will improved significantly.At the same time,it will effectively reduce the occurrence of pancretogenic diabetes since the surgery retains some function of the islet cells.