Therapeutic value of immune cell therapy based on T memory stem cells and central memory T cells for hematological malignancies
10.3760/cma.j.issn.1009-9921.2017.02.003
- VernacularTitle:基于记忆性干性T细胞和中心记忆性T细胞的细胞免疫治疗在血液肿瘤治疗中的价值
- Author:
Ling XU
;
Yangqiu LI
- Keywords:
Hematologic neoplasms;
T cell immunotherapy;
T memory stem cells;
Central memory T cells;
America Society of Hematology Annual Meeting
- From:
Journal of Leukemia & Lymphoma
2017;26(2):71-73
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,cellular immune therapy represented by antigen-chimeric receptor T cells (CAR-T) has made a great breakthrough in the treatment of hematological malignancies.T memory stem cells (TSCM) and central memory T cells (TCM) can be used as most powerful carrier for T cell immunotherapy,however,how to regulate their differentiation in vitro and in vivo as well as how to construct a strong treatment system while without potential side effect become quite interesting.This article summarized the studies from the 58th America Society of Hematology Annual Meeting regarding to values and associated research progress about TsCM and TCM in hematological malignancies.
