Evaluation of Renal Peripheral Inflow Perfusion in Patients with Nephrotic Syndrome by Region of Interest Quantification
10.3969/j.issn.1005-5185.2017.02.015
- VernacularTitle:彩色多普勒感兴趣区定量技术评价肾病综合征患者肾皮质血流灌注
- Author:
Liu HONG
;
Jing WANG
;
Mingxing XIE
- Keywords:
Nephrotic syndrome;
Ultrasonography,Doppler,color;
Kidney cortex;
Hemoperfusion;
Hemodynamics
- From:
Chinese Journal of Medical Imaging
2017;25(2):131-135
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate renal cortical blood perfusion in patients with nephrotic syndrome (NS) by region of interest (ROI) quantification.Materials and Methods Twenty-one patients with NS treated at Wuhan Union Hospital from September 2014 to January 2015 (NS group) and twenty-nine matched healthy subjects (control group) were enrolled in our study.High frequency blood flow dynamic images of the left kidney for all the subjects were acquired by color Doppler (Philips iU22).Resistance index (RI) of interlobar artery,arcuate artery and interlobular artery were measured.Vascularization index (VI),flow index (FI),vascularization flow index (VFI) were further analyzed by ROI quantification at Q-LAB work station.Results ① The signals of renal cortical blood flow in NS patients were sparse and slim;while the signals in the control group were continuous,most of which reached the edge of renal cortical.② No statistical differences of RI values of interlobar artery and interlobular artery were found between the two groups (P＞0.05);③ The renal cortical blood perfusion in the NS patients decreased significantly compared with that in control group,and the renal cortical VI,FI and VFI values in NS group were significantly lower (P＜0.01).④ Bland-Altman analysis showed that there was good repeatability in the measurement of renal cortical VI,FI and VFI.Conclusion Color Doppler flow imaging combined with RO1 quantitative technique can assess renal cortical blood perfusion accurately,which provides diagnostic information for early detection of renal damage.
