Epidemiology of thyroid nodules and thyroid function in southern mountainous areas of Ningxia Hui Autonomous Region
10.3760/cma.j.issn.1674-0815.2017.02.013
- VernacularTitle:宁夏南部山区甲状腺结节和甲状腺功能异常的流行病学调查
- Author:
Ting WANG
;
Haili XUE
;
Qingling LU
;
Haidong ZHANG
;
Jinlian WANG
;
Xueru LI
;
Bing QI
;
Zhijie MA
;
Xuefeng MA
;
Xuhong HOU
;
Qingyi SUN
;
Weiping JIA
;
Lanjie HE
- Keywords:
Thyroid nodules;
Thyroid function;
Southern mountains;
Prevalence
- From:
Chinese Journal of Health Management
2017;11(2):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of thyroid nodules and thyroid dysfunction in southern mountainouss areas of Ningxia.Methods A cross-sectional study was conducted among a representative sample of 10 639 adults in Jingyuan county with a population proportionate sampling method.High-resolution ultrasound was used to examine the thyroid and fasting blood specimens were collected in the morning for measurement of TSH,FT4,FT3.Chi-square test and spearman rank correlation analysis were used for statistical analysis.Results The prevalence of thyroid nodules was 29.08%,the sex-and age-adjusted rate was 27.17%.The prevalence of thyroid nodules was higher in women than in men (32.68% vs.24.88%,x2=76.029 2,P<0.001) and age was positively associated with thyroid nodules (r=0.272,P<0.001).The rate of thyroid dysfunetion,subclinical hypothyroidism,subclinical hyperthyroidism,hypothyroidism,hyperthyroidism were 17.39%,13.00%,0.42%,0.96%,3.01%,respectively.The prevalence of thyroid nodules was higher in abnormal TSH group than in normal TSH group (39.44% vs.27.24%,x2=95.624 0,P<0.001).The level of THS,FT3,FT4 in thyroid nodules group differed fromn control group (Z=-9.144,P<0.001;Z=-6.140,P<0.001;Z=-1.997,P=0.046).Conclusion The prevalence of thyroid nodules and thyroid dysfunction were higher in southern mountainous areas of Ningxia.The relationship between thyroid nodules and thyroid function needs further research.We should pay attention to the early screening and diagnosis of thyroid nodules in mountainous areas.