Diagnosis and treatment of functional pancreatic dndocrine tumor
10.3760/cma.j.issn.1674-6090.2016.06.006
- VernacularTitle:功能性胰腺内分泌肿瘤的诊治分析
- Author:
Junfeng YANG
;
Dongzhi ZHOU
;
Yangyang GU
;
Cong SHA
;
Aijun YUAN
- Keywords:
Functional pancreatic endocrine tumor;
Pancreatic resection;
Laparoscopic surgery
- From:
Chinese Journal of Endocrine Surgery
2016;10(6):465-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and management of functional pancreatic endocrine tumor.Methods Clinical data of 19 cases of functional pancreatic endocrine tumor were retrospectively analyzed.Results 15 cases of insulinoma,2 cases of gastrinoma and 2 cases of glucagonoma were qualitatively diagnosed.The positive rate of preoperative diagosis for type B ultrasonic inspection,CT,MRI,EUS,selective portovenous sampling and intraoperative type B ultrasonic inspection was 15.8% (3/19),67.5% (10/16),71.4% (5/7),87.5% (7/8),100%(2/2) and 85.7%(6/7) respectively.Of the total 19 cases,7 cases underwent open surgery,11 cases unde rwent laparoscopic surgery,and one case didn't undergo any surgery as liver metastasis had occurred when glucagonoma was diagnosed.The operation methods included tumor enucleation (n=13),distal pancreatic resection (n=3),distal pancreatic resection plus splenectomy (n=1),and pancreatic head resection with duodenum preserved (n=1).Conclusions The measurement of serum insulin,gastrin and glucagon is the main basis for qualitative diagonosis of pancreatic endocrine tumor.Two stage spinal CT thin scanning is the main method for tumor location.Intraoperative type B ultrasonic inspection is the supplement to preoperative location.Tumor enucleation is the main choice of treatment.