The influence of coagulation dysfunction to the prognosis in the critically ill patients of emergency room
10.3760/cma.j.issn.1671-0282.2017.04.018
- VernacularTitle:急诊危重症患者凝血功能异常对预后的影响
- Author:
Tao WANG
;
Shuo WANG
;
Chunsheng LI
;
Ziren TANG
- Keywords:
Coagulation;
D-dimer;
APACHE Ⅱ;
Blood platelet;
Fibrinogen;
Emergency;
Critically ill;
Prognosis
- From:
Chinese Journal of Emergency Medicine
2017;26(4):446-450
- CountryChina
- Language:Chinese
-
Abstract:
Objective This research investigated the coagulation of critically ill patients for predicting the prognosis of 28 day in a university hospital emergency room.Methods A prospective investigation was done in the emergency room of Beijing Chao-Yang Hospital,Capital Medical University from June 2015 to May 2016,and 28-day mortality was recorded.Whole blood cell analysis,blood gas analysis and clotting test were done and repeated after patients in hospital.Results A total of 1 992 patients were enrolled,and divided into two groups:survival (n =1 522) and dead (n =470).No significant difference of age,gender,body mass index and disease composition were found between the two groups (P ＞0.05).APACHE Ⅱ of the survival and dead groups were (12.11 ±4.12) and (21.15 ± 5.55) respectively.D-dimer and platelet account of the dead group were M (Qr) 265 (0,718) μg/L and (208.16±89.87) × 109/L-1 respectively,significant differences were found between the two groups (P ＜ 0.05).Coagulation was found deteriorated progressively in the dead group,whereas improved in the survival group.The risk factors of poor prognosis,which were the increased APACHE Ⅱ and D-dimer,were detected by Logistic analysis and ROC curve,especially the D-dimer.Conclusions Coagulation abnormalities were found in the critically ill patients of emergency room.The increasing of D-dimer is one of the risk factors of poor prognosis.
