Association between prostasomes and prostate disease
10.3760/cma.j.issn.0254-9026.2017.01.026
- VernacularTitle:前列腺小体与前列腺疾病的关系
- Author:
Yan ZENG
;
Qun LU
- Keywords:
Prostatic neoplasms;
Prostatitis
- From:
Chinese Journal of Geriatrics
2017;36(1):102-105
- CountryChina
- Language:Chinese
-
Abstract:
Prostasomes are one of the subcellular structures secreted by prostatic epithelial cells.They present in human semen as membranous vesicles with average diameter of 150nm(40-500nm).440 proteins have been identified in human prostasomes and possess many physical functions.Prostasomes may not only exert a motility function for spermatozoa by delaying the acrosome reaction,but also have immune regulatory function,antibacterial and antioxidant characteristics.Prostasomes can be isolated from the serum and urine,and they present both in normal and prostatic cancer tissues.Prostasome can be a special prostatic biomarker and has a close association with prostatitis and prostate cancer.
