Anti-infective reconstituted bone xenograft combined with external fixator for treatment of posttraumatic long bone infection in lower extremities
10.3760/cma.j.issn.1001-8050.2017.02.013
- VernacularTitle:抗感染重组合异种骨联合外固定架治疗下肢长骨创伤后骨感染
- Author:
Long BI
;
Zhi YUAN
;
Jian LIU
;
Guolin MENG
;
Yan LI
;
Jiakai GAO
- Keywords:
Osteomyelitis;
External fixators;
Anti-infection
- From:
Chinese Journal of Trauma
2017;33(2):153-158
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the long-term efficacy of anti-infective reconstituted bone xenograft (ARBX) combined with external fixation of posttraumatic long bone infection in lower extremities.Methods This retrospective case series study included 36 patients with posttraumatic long bone infection in lower extremities followed up for more than 18 months after receiving one-stage ARBX bone grafting combined with ring external fixation from January 2004 to December 2013.There were 21 male and 15 female patients,at the age of 19-72 years (mean,35.8 years).Multiple fractures were seen in 24 patients and single fractures in 12 patients.Bone and functional results were evaluated using the association for the study and application of the method of Ilizarov (ASAMI) classification.Results Follow-up ranged from 18 to 72 months (mean,38 months).Bone union was seen in 33 cases in a mean period of 5.2 months,and infection was completely cured.Length of limbs in all patients reached the expected extension length with the bone extension length of 3-10 cm (mean,5.2 cm).All the extended areas showed bone healing.According to the ASAMI classification,bone result was excellent in 20 patients,good in 13 and fair in 3,with the excellent and good rate of 92％,and limb function recovery was excellent in 18 patients,good in 11 and fair in 7,with the excellent and good rate of 81％.Conclusion ARBX adjuvant external fixator treatment of posttraumatic long bone infection in lower extremities improves bone healing rate and limb function recovery rate and shortens bone healing time at one stage.
