New advancements of C3 glomerulopathy
10.3760/cma.j.issn.1008-1372.2017.01.010
- VernacularTitle:C3肾小球病研究新进展
- Author:
Chang WANG
;
Chao CHEN
;
Lin SUN
- Keywords:
Glomerulonephritis;
Complement C3;
Complement C3b
- From:
Journal of Chinese Physician
2017;19(1):32-37
- CountryChina
- Language:Chinese
-
Abstract:
C3 glomerulopathy (C3G) is referred to disease which is out of control of complement activation,degradation and deposition,then leads to predominant C3 deposition in glomerular and glomerular injury.The study found that C3b amplification in the circulation and/or glomerular basement membrane were the key factors that cause immune disorders.Combined with clinical and experimental research,this paper mainly discusses the pathogenesis,clinical characteristics,and treatment of the disease.
