Advances in clinical immunology research on chronic hepatitis B
10.3760/cma.j.issn.1008-1372.2017.01.003
- VernacularTitle:慢性乙型肝炎临床免疫学研究进展
- Author:
Wei YUAN
;
Weiming YAN
;
Qin NING
- Keywords:
Hepatitis B,chronic/IM;
Review
- From:
Journal of Chinese Physician
2017;19(1):7-13
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,clinical immunology has an increasing variety of prominent applications in the field of chronic hepatitis B infection.On one hand,the discovery and identification of the mechanisms of pathogen recognition by the innate immune system,novel immune cell subpopulations and immunoregulatory pathways further enriched the immunological pathogenesis of chronic hepatitis B.On the other hand,the development of new immunotherapy strategies aimed at reconstructing the antiviral immunity,including agonists of Toll like receptors,immune cell therapies and therapeutic vaccines,have provided several new targets for the optimization of antiviral therapy strategies and brought new opportunities for patients of chronic hepatitis B to obtain HBsAg clearance and clinical cure.
