Research progress of ischemic cerebrovascular disease and S-100β MMP-9

VernacularTitle:缺血性脑血管病与S-100β、MMP-9的研究进展
Author: Liping YAO ; Qiming YANG
Keywords: Brain ischemia/ME; S100 proteins/ME; Matrix metalloproteinase 9/ME; Review
From: Journal of Chinese Physician 2016;18(12):1914-1917
CountryChina
Language:Chinese
Abstract: Ischemic cerebrovascular disease is a common and frequently occurring disease in the elderly.It has the characteristics of high disability rate,high mortality rate,and high recurrence rate,which seriously threatens the life and health of the elderly.At present,clinical diagnosis and evaluation are mainly based on medical history,neurological symptoms and signs and imaging examination.The incidence of ischemic cerebrovascular disease is rapid,the existing diagnostic methods have different degrees of hysteresis and limitations in the diagnosis time.Related clinical study found that in the process of ischemic cerebrovascular disease accompanied by serum S-100 beta,matrix metalloproteinase-9 (MMP-9)-related indicators of change.This article reviews the recent progress of S-100 beta and MMP-9 in ischemic cerebrovascular disease.