Diagnostic value of ultrasonography in predicting neck lymph node metastasis in Hashimoto's thyroiditis with papillary carcinoma
10.3760/cma.j.issn.1004-4477.2016.11.011
- VernacularTitle:超声诊断桥本甲状腺炎合并甲状腺乳头状癌颈部淋巴结转移的临床价值
- Author:
Qian ZHU
;
Jiawei LI
;
Shichong ZHOU
;
Cai CHANG
;
Min CHEN
;
Yiwu FAN
- Keywords:
Ultrasonography;
Hashimoto's disease;
Thyroid neoplasms;
Lymphatic metastasis
- From:
Chinese Journal of Ultrasonography
2016;25(11):962-965
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of ultrasonography for neck lymph node metastasis in papillary thyroid carcinoma(PTC) and Hashimoto's thyroiditis(HT) coexistent with PTC.Methods Two hundred and seventy-eight patients who accepted thyroid surgery were retrospectively reviewed for the pre-operative ultrasonographic and post-operative pathological reports.All patients were confirmed as PTC by surgery and pathology.According to the presence of HT confirmed in pathology,all patients were divided into two groups:group of PTC and group of HT with PTC.The status of neck lymph node metastasis and the diagnostic value of pre-operative ultrasound in detecting neck lymph node metastasis were studied.Results There were 185 cases in the group of PTC,and the rate of neck lymph node metastasis was 59.5 ％;while there were 93 cases in the group of HT with PTC,in which the rate of neck lymph node metastasis was 45.2％.The difference between the two groups in lymph node metastasis was statistically significant (P =0.024).The predictive accuracy of pre-operative ultrasound for central neck lymph node was 53.9％ in the group of PTC,which was statistically higher than 18.8％ in the group of HT with PTC(P =0.01).The predictive accuracy of pre-operative ultrasound for lateral neck lymph node was 79.4％ in the group of PTC,which had no statistical difference with that in the group of HT with PTC (73.1％,P =0.565).Conclusions The neck lymph node metastasis in PTC patients occurs more frequently than that in PTC patients with HT.The value of pre-operative ultrasound examination is lower for the detection of central lymph node metastasis,especially in PTC patients with HT;while ultrasound is more sensitive and accurate for lateral lymph node detection regardless of the existence of HT.
