Effect of Needle Revision of Failed Filtering Blebs with Different Concentrations of Mitomycin C.
10.3341/jkos.2008.49.6.951
- Author:
Kyeong Jin WOO
1
;
Sungmin HYUNG
Author Information
1. Department of Ophthalmology, School of Medicine, Chungbuk National University, Chungbuk, Korea. smh@chungbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Filtering bleb;
Mitomycin C;
Needle revision
- MeSH:
Anterior Chamber;
Blister;
Conjunctiva;
Eye;
Follow-Up Studies;
Hemorrhage;
Hyphema;
Intraocular Pressure;
Mitomycin;
Needles;
Risk Factors;
Sutures
- From:Journal of the Korean Ophthalmological Society
2008;49(6):951-957
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the efficacy and the risk factors for failure and complications of mitomycin C (MMC)-augmented needle revision (NR) of failed filtering blebs. METHODS: Thirty eyes whose intraocular pressure (IOP) did not decrease after the cutting of scleral flap sutures were recruited. NR was performed with a 26-gauge needle under a slit-lamp. Immediately following NR, all eyes received a subconjunctival injection of 0.1 ml of 0.02 mg/ml (group A) or 0.1 mg/ml (group B) MMC at the adjacent conjunctiva. The mean follow-up period after the last needle revision was 13.2+/-4.2 months. RESULTS: The mean IOP decreased from 25.7+/-10.6 mmHg before surgery to 13.7+/-2.5 mmHg at the last follow-up in group A and from 24.1+/-6.8 mmHg to 17.7+/-8.6 mmHg in group B (group A: p=0.001, group B: p=0.065). Subconjunctival hemorrhage, hyphema, and a shallow anterior chamber appeared in most cases. However, choridal detachment and avascular changes of the conjunctiva were observed in group B. CONCLUSIONS: IOP decreased in both groups A and B, but severe complications appeared only in group B. NR followed by a subconjunctival injection of 0.02 rather than 0.1 mg/ml is a safe and effective method.
