Causes of amenorrhea in Korea: Experience of a single large center.
10.5653/cerm.2014.41.1.29
- Author:
Su Kyoung KWON
1
;
Hee Dong CHAE
;
Kyung Hee LEE
;
Sung Hoon KIM
;
Chung Hoon KIM
;
Byung Moon KANG
Author Information
1. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. hdchae@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Amenorrhea;
Gonadal dysgenesis;
Polycystic ovary syndrome;
Causes
- MeSH:
Amenorrhea*;
Androgen-Insensitivity Syndrome;
Chungcheongnam-do;
Female;
Gonadal Dysgenesis;
Gynecology;
Humans;
Hypogonadism;
Korea*;
Male;
Medical Records;
Obstetrics;
Polycystic Ovary Syndrome;
Retrospective Studies
- From:Clinical and Experimental Reproductive Medicine
2014;41(1):29-32
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To investigate the causes of amenorrhea in Korean women. METHODS: Medical records from 1,212 women with amenorrhea who visited the Department of Obstetrics and Gynecology, Asan Medical Center, between January 1989 and December 2011 were retrospectively reviewed. Amenorrhea was categorized as either primary or secondary. RESULTS: Primary amenorrhea was identified in 132 of the patients (10.9%) and secondary amenorrhea in 1,080 (89.1%). The most frequent causes of primary amenorrhea were gonadal dysgenesis (28.0%, 37/132); Mayer-Rokitansky-Kuster-Hauser syndrome (20.0%, 27/132); and constitutional delay and androgen insensitivity syndrome (8.3%, 11/132; 8.3%, 11/132, respectively). Secondary amenorrhea was due to polycystic ovary syndrome (48.4%, 523/1,080); premature ovarian insufficiency (14.0%, 151/1,080); and nutrition-related hypogonadotropic hypogonadism (8.3%, 90/1,080). CONCLUSION: In this retrospective study, gonadal dysgenesis was the most common cause of primary amenorrhea and polycystic ovary syndrome was the most common cause of secondary amenorrhea in Korean women.
