Study on the Preparation Technology of Angelica sinensis Powder and Screening for the Optimal Particle Size
10.6039/j.issn.1001-0408.2016.25.30
- VernacularTitle:当归粉制备工艺研究及最优粉碎粒径筛选
- Author:
Mingju GAO
;
Ni MA
;
Guangquan FENG
;
Yongjian SHAO
;
Yong DIAO
- Publication Type:Journal Article
- Keywords:
Angelica sinensis powder;
Preparation technology;
Particle size;
Volatile oil;
Ferulic acid
- From:
China Pharmacy
2016;27(25):3555-3557
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the preparation technology of Angelica sinensis powder and conduct screening for the op-timal particle size thereof. METHODS:With the contents of volatile oil and ferulic acid as the indexes,screening was conducted for the optimal drying temperature,dry welding time and particle size of the crude drug A. sinensis,and the stabilities of the A. si-nensis powder with different particle sizes which was packed by simulating that sold in the market were investigated. The verifica-tion tests on the preparation technology were conducted. RESULTS:The optimal conditions for preparing the crude drug A. sinensis were as follows as drying temperature of 60-70℃,drying for 4.5-5 hours and being crushed into moderate-sized powder;the stabil-ity of the moderate-sized powder which was packed by simulating that sold in the market was the best. In the verification tests on the preparation technology,the average content of the volatile oil was 0.46 ml/g,with RSD of 0.034%(n=3);the average con-tent of the ferulic acid was 0.123 μg/ml,with RSD of 0.026%(n=3). CONCLUSIONS:The optimized technology is stable and feasible,and the stability of the moderate-sized A. sinensis powder is the best.
