Optimization of Water Extraction Technology for Shenqi Yiqi Capsules with Multi-index Comprehensive Score-orthogonal Test
10.6039/j.issn.1001-0408.2016.22.34
- VernacularTitle:多指标综合评分-正交试验法优化参芪益气胶囊的水提工艺
- Author:
Xiaojing NIU
;
Hui ZHANG
;
Xiaolong LIU
;
Wenxin ZHANG
;
Xiaoying DUAN
- Publication Type:Journal Article
- Keywords:
Shenqi yiqi capsules;
Extraction technology;
Orthogonal test;
Multi-index comprehensive score
- From:
China Pharmacy
2016;27(22):3139-3141
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize water extraction technology of Shenqi yiqi capsules. METHODS:The water extraction technology of Shenqi yiqi capsules was optimized by L9(34)orthogonal test with amount of water added,decoction times and decoc-tion time as factors using the extraction rate of astragaloside,calyosin-7-O-β-D-glycoside,icariin and bergenin as index,and the verification test was made. RESULTS:The best extraction technology was as follows as 8-fold water,decocting for 3 times,2 h each time;comprehensive score of 3 batches of samples in validation test were 98.95,99.71 and 99.98(RSD<2%,n=3). CON-CLUSIONS:The water extraction technology optimized by multi-index comprehensive score-orthogonal test is stable,scientific and reasonable.
