The expression feature and clinical significance of plasma protein C in patients with cancer Before and after PICC catheter
10.3969/j.issn.1673-4130.2016.18.014
- VernacularTitle:肿瘤患者 PICC置管前后血浆蛋白C变化特点及意义
- Author:
Peifen LU
;
Xu CHENG
;
Jinhu WANG
;
Xiangtao PAN
- Publication Type:Journal Article
- Keywords:
PICC;
cancer;
plasma protein C;
D-dimer
- From:
International Journal of Laboratory Medicine
2016;37(18):2543-2544
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression feature and clinical significance of plasma Protein C(PC) in pre‐PICC placement and post‐PICC placement in patients with cancer .Methods The levels in plasma of PC was tested by ELISA in patients with cancer in one day before PICC placement ,in one day ,30 day ,and 90 day after PICC placement ,the change of feature and clinical signifi‐cance was analyzed .Results The levels of PC in one day after PICC placement were 3 .74 ± 1 .99 μg/L ,the levels was lower than the levels of in one day before ,and in 30 ,90 day after PICC placement ,which were 5 .00 ± 2 .40 ,4 .78 ± 2 .41 and 5 .35 ± 2 .71 μg/L (q=3 .74 ,2 .85 and 4 .58 respectively ,P<0 .05);There were no statistical significance both in D‐D levels and PLT count among pre‐PICC and post‐PICC placement(P>0 .05);There were no correlation both PC levels and D‐D levels ,and both PC levels and PLT count(r= -0 .024 1 and 0 .111 0 ,all P>0 .05) .Conclusion The PC levels in one day after PICC placement were lower ,but there were no correlation both PC and D‐D ,and PLT .PICC catheter were safety .
