Comparative Study of Separation on Phenolic Acids Components by Nanofiltration Process
10.6039/j.issn.1001-0408.2016.21.27
- VernacularTitle:中药酚酸类成分的纳滤分离行为对比研究
- Author:
Qiyang QU
;
Shiqi FANG
;
Guoping PENG
;
Hongyang LI
;
Hao SHI
;
Jiamei GU
;
Cunyu LI
- Publication Type:Journal Article
- Keywords:
Nanofiltration membrane;
Phenolic acids;
Rejection rate;
Molecular weight
- From:
China Pharmacy
2016;27(21):2965-2968
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effect of polyamide on the separation on phenolic acids components by nanofiltra-tion process. METHODS:Phenolic acids components were selected as targets,extracted from the Salvia miltiorrhiza,Lonicera ja-ponica or intermediate preparations (tea polyphenols) with water,and filtered with membranes with different pore sizes. The con-tent changes of components were analyzed by HPLC. RESULTS:Danshensu,protocatechuic aldehyde and caffeic acid could better transmit nanofiltration membranes with 3 different pore sizes;with the decrease of pore size,the rejection rates of neochlorogenic acid,chlorogenic acid,rosmarinci acid,ECG and EGCG grew in different levels. But salvianolic acid B was almost retained by the membrane with low molecular weight except 600-800 Da. CONCLUSIONS:Molecular weight importantly influenced nanofiltra-tion separation on phenolic acid components;nanofiltration has a good prospect in enrichment of phenolic acids components.
