Rapid Identification of Sanjiu Weitai Granule and Quantitative Analysis of Moisture by Near-infrared Spec-troscopy
10.6039/j.issn.1001-0408.2016.18.35
- VernacularTitle:近红外光谱法快速鉴别三九胃泰颗粒及其水分定量分析
- Author:
Yan YAN
;
Guo YIN
;
Kaishuang LIU
;
Jue WANG
;
Tiejie WANG
- Publication Type:Journal Article
- Keywords:
Sanjiu weitai granule;
Near-infrared spectroscopy;
Conformity test model;
Quantitative model of moisture
- From:
China Pharmacy
2016;27(18):2551-2554
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for the rapid identification of Sanjiu weitai granule and quantitative analysis of moisture. METHODS:Near-infrared (NIR) spectroscopy was adopted. 38 batches of Sanjiu weitai granule were collected,NIR spectrum was determined by integrating sphere diffuse-reflectance. Conformity test model was performed by comparing consistency index(CI)value and CI limit,and quantitative model of moisture was established using partial least squares(PLS)algorithm. RE-SULTS:When CI value was less than 6,the established model can accurately distinguish Sanjiu weitai granule,the model was proven feasible;the correlation coefficient (r2) of quantitative model was 97.44,the root mean square error of cross validation (RMSECV) was 0.453,the root mean square error of prediction (RMSEP) was 0.748. CONCLUSIONS:The method is simple and rapid without destroying,which can be applied to fast screening of Sanjiu weitai granule in site and fast determination of mois-ture content.
