Progress in long non-coding RNA in hematopoiesis
10.3760/cma.j.issn.1009-9921.2016.09.017
- VernacularTitle:长链非编码RNA在造血系统中的研究进展
- Author:
Lan ZHANG
;
Weihua ZHANG
- Publication Type:Journal Article
- Keywords:
Long non-coding RNA;
Hematopoiesis
- From:
Journal of Leukemia & Lymphoma
2016;25(9):572-576
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs (lncRNAs) , which are closely related with human critical illness, can regulate gene expression and involve the physiological and pathological processes on epigenetic, transcriptional and post-transcriptional levels through several mechanisms. LncRNAs also play important regulation roles in the maturation and differentiation process of hematopoietic cell. Besides, in-depth exploration of their mechanism will provide new ideas for the diagnosis and treatment of blood diseases.