The relationship between the doses in parenteral nutrition and short term outcomes in very low birth weight ;infants
10.3969/j.issn.1000-3606.2016.09.004
- VernacularTitle:极低出生体质量儿肠外营养素剂量与其近期转归的相关性
- Author:
Yu CHENG
;
Jing LI
;
Yi FENG
;
Fei BEI
- Publication Type:Journal Article
- Keywords:
very low birth weight infants;
parenteral nutrition;
complication;
extrauterine growth retardation
- From:
Journal of Clinical Pediatrics
2016;34(9):657-660
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of different doses of amino acids and fat emulsions in parenteral nutrition on the incidence of complications and prognosis in very low birth weight infants (VLBWI). Methods The clinical data of 328 VLBWI who received nutrition support therapy for at least 5 days starting in 72 h after birth during January 2005 to December 2014 , were retrospectively analyzed. According to the dosage in parenteral nutrition, patients were divided into low-dose group and high-dose group. The incidence of complications and prognosis between two groups were compared. Results There were 204 cases in low-dose group and 124 cases in high-dose group. Compared with the low-dose group, the incidence of complications was lower in high-dose group during hospitalization and the incidence of intracranial hemorrhage was reduced most;the incidence of developmental retardation was lower at discharge;the overall incidence of metabolic complications of parenteral nutrition was higher, among which the incidence of high blood glucose, electrolyte disturbance and cholestasis were increased and the incidence of hypoglycemia was lower, and the differences were all statistically signiifcant (P??0 . 05 ). Conclutsions VLBWI can tolerate early aggressive parenteral nutrition which can reduce the incidence of extrauterine growth retardation and premature complications.
