Effects Analysis of Special Rectification of Antibiotics for Prophylactic Use in Perioperative Period of Per-manent Cardiac Pacemaker Implantation in Our Hospital
10.6039/j.issn.1001-0408.2016.17.10
- VernacularTitle:我院永久性心脏起搏器植入术围术期预防使用抗菌药物专项整治效果分析
- Author:
Xiaojuan ZHANG
;
Jiyan CHEN
;
Silin CHEN
;
Min YANG
- Publication Type:Journal Article
- Keywords:
Permanent cardiac pacemaker implantation;
Perioperative period;
Antibiotics;
Prophylactic application;
Special rec-tification
- From:
China Pharmacy
2016;27(17):2333-2335
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for rational prophylactic application of antibiotics in perioperative period of per-manent cardiac pacemaker implantation. METHODS:600 cases performed permanent cardiac pacemaker implantation in 2010(be-fore rectification),2012(during rectification)and 2014(after rectification)were randomly sampled from our hospital,and divided into control group,intervention group one and intervention group two. The prophylactic application of antibiotics was investigated and analyzed in 3 groups. RESULTS:For control group,intervention group one and intervention group two,the rates of rational type selection of antibiotics for prophylactic use were 7.25%,31.00% and 91.96%,respectively. The rates of rational medication timing of antibiotics for prophylactic use were 0,100% and 100%;average duration of prophylactic use decreased from (3.6 ± 1.2)d before intervention to(1.1±0.5)d and(1.0±0.2)d. There was no statistical significance in the incidence of postoperative infection(P>0.05). Compared with control group,average drug cost,antibiotics cost and drug ratio decreased significantly in in-tervention group,with statistical significane (P<0.05). CONCLUSIONS:Antibiotics special rectification is effective and improve the rational application of antibiotics in our hospital.