Determination of Residual Palladium in Bendamustine Hydrochloride by GFAAS
- VernacularTitle:石墨炉原子吸收分光光度法测定盐酸苯达莫司汀中钯的残留量
- Author:
Dejun CHEN
;
Dongmei ZHANG
;
Song WANG
;
Xiao LING
- Publication Type:Journal Article
- Keywords:
Bendamustine hydrochloride;
Residual palladium;
GFAAS
- From:
China Pharmacist
2016;19(9):1808-1809
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop a method for the determination of palladium in bendamustine hydrochloride by GFAAS. Meth-ods:The sample was destroyed by heat, and the content of palladium was determined by GFAAS with the detection wavelength of 247. 6 nm. Results:The absorbance and the content of palladium showed a good linear relationship within the range of 20-60 ng· ml-1(r=0. 998 4). The average recovery of palladium was 102. 9%(RSD=1. 7%, n=9). Conclusion: The method is sensitive and simple, which can be used for the determination of palladium in bendamustine hydrochloride.
