Effect and Influence of Homocysteine and Cystatin C in Type 2 Diabetes Patients treated by Shuxuening In-jection Combined with Gliclazide
- VernacularTitle:舒血宁注射液联合格列齐特治疗2型糖尿病的疗效及对同型半胱氨酸和胱抑素C水平的影响
- Author:
Qiaoyun LV
;
Xiaohua LI
;
Zihai WEN
- Publication Type:Journal Article
- Keywords:
Shuxuening injection;
Type 2 diabetes;
Homocysteine;
Cystatin C;
Gliclazide
- From:
China Pharmacist
2016;19(9):1697-1699
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect and influence of homocysteine and cystatin C in type 2 diabetes patients treated by Shuxuening injection combined with gliclazide. Methods: Type 2 diabetic patients were randomly divided into observation group and control group,and there were 30 cases in each group. The control group was given gliclazide hypoglycemic treatment, on the basis of the observation group to combined with Shuxuening injection. The course of treatment was 2 weeks. Efficacy , adverse drug reactions ,Ho-mocysteine ( Hcy) , Cystatin C ( CysC) and blood glucose ( FBG, PB) level change of two groups patients before and after treatment were compared. Results:The total effective rate of the observation group was 96. 67%, which was significantly higher than that of the control group (P<0. 05). After treatment,blood glucose and Hcy, CysC levels of the two groups of patients were significantly de-creased compared with before treatment (P<0. 05),and those of the observation group was much lower(P<0. 05). The incidence of adverse drug reactions between the two groups had no significant difference(P>0. 05). Conclusion:Shuxuening Injection on patients with type 2 diabetes mellitus has good curative effect, it can effectively reduce homocysteine and cystatin C levels, better control of blood glucose.
