Important Roles of Pharmaceutical Excipients Standards and Guidelines System Construction in Excipients Regulatory Reform in China
- VernacularTitle:药用辅料标准和技术体系建设对我国辅料监管改革的重要作用
- Author:
Ying WANG
;
Peng HAN
;
Xianglin ZHANG
- Publication Type:Journal Article
- Keywords:
System reform;
DMF system;
Excipients standards;
Guidelines system;
Countermeasures and suggestions
- From:
China Pharmacist
2016;19(9):1726-1730
- CountryChina
- Language:Chinese
-
Abstract:
Pharmaceutical excipients are implementing registration and approval management in our country. As the disadvantages of the registration system appearing continuously, the demand for reform is getting higher and higher. The cry for drug master files ( DMF) model instead of registration and approval management is becoming more prominent. Based on the understanding of DMF sys-tem, the article discussed the positive roles of the excipients standards and guidelines construction in DMF implementation using phar-maceutical excipients supervision experience in the United States as the reference and starting from the standards and guidelines system of excipients, which aimed to provide suggestions for the supervision and management of pharmaceutical excipients, and improve the quality and safety of pharmaceutical excipients and drugs.
