Research Progress in Intravesical Chemotherapy for Non-muscle-invasive Bladder Cancer
- VernacularTitle:非肌层浸润性膀胱癌的灌注化学疗法研究进展
- Author:
Lixiang REN
;
Baoshan CHAI
- Publication Type:Journal Article
- Keywords:
Non-muscle-invasive bladder cancer;
Intravesical chemotherapy;
Drug delivery system;
Treatment strategy
- From:
China Pharmacist
2016;19(9):1747-1751
- CountryChina
- Language:Chinese
-
Abstract:
Bladder cancer is the most common malignant solid tumor in urinary system. More than 75% cases of bladder cancer have been diagnosed as non-muscle-invasive bladder cancer ( NMIBC ) . Transurethral resection of bladder tumor ( TURBT ) is the standard method for the diagnosis and treatment for bladder cancer, however, due to its problem of recurrence, adjuvant intravesical therapy with either immunotherapy or chemotherapy has been used to reduce recurrence and achieve better efficacy for the patients in appropriate stages. The review focused on current progress in chemotherapy agents, targeted bladder drug delivery systems and treat-ment strategies for NMIBC, which would provide guidance for clinical intravesical chemotherapy.