Fuzzy Cluster Analysis of Compositae Involved in Effective Patent of TCM Extract Combination on Drug Properties
10.6039/j.issn.1001-0408.2016.16.18
- VernacularTitle:基于中药药性的中药提取物组合相关有效专利中菊科中药的模糊聚类分析
- Author:
Jiangxue CHENG
;
Shiying XIAO
;
Tonghua LIU
- Publication Type:Journal Article
- Keywords:
Compositae;
TCM;
Extract;
Fuzzy cluster;
Property;
Flavor;
Meridian tropism
- From:
China Pharmacy
2016;27(16):2221-2224
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To classify the drug properties of Compositae involved in effective patent of TCM extract combina-tion. METHODS:Property,flavor and the meridian tropism of TCM were used as the parameters;by computer analysis software, fuzzy cluster analysis was conducted from Compositae mostly involved in effective patent of TCM extract combination which ap-proved before Jan. 1st in 2015 and kept till May 30th in 2015. RESULTS & CONCLUSIONS:27 ingredients of Compositae were involved with the functions as protecting liver almost. They were classified into 5 categories. The first category included 10 ingredi-ents as Dendranthema morifolium which were cold,bitter to taste,and in the liver and lung meridian,and all of them contained flavonoids compounds;the second category included 3 ingredients as Gnaphalium affine of which flavonoids compounds were main medicinal components;the third category included 5 ingredients as Atractylodes lancea which could protect liver and contained vola-tile oil;the forth category included 4 ingredients as Tussilago farfara which showed anti-inflammatory and anti-tumor effect;the fifth category included 5 ingredients as Erigeron breviscapus which contained ingredients for cardiovascular disease. Those catego-ries were similar not only in property,flavor and the meridian tropism,but also in active ingredients and effects. The researchers should further research TCM of which pharmacologic action are not well understood,by means of make reference to known TCM in the same category,and make preparation to save time and enlarge medicinal resource.
