Clinical Observation of Salbutamol Sulfate by Atomized Inhalation in the Treatment of Pediatric Asthmatic Disease
10.6039/j.issn.1001-0408.2016.15.09
- VernacularTitle:硫酸沙丁胺醇雾化治疗小儿喘息性疾病的临床观察
- Author:
Yong LIN
;
Jingjun PENG
;
Wencheng LI
;
Bo HUANG
- Publication Type:Journal Article
- Keywords:
Salbutamol sulfate;
Atomization;
Pediatric asthmatic disease;
Efficacy;
Safety
- From:
China Pharmacy
2016;27(15):2043-2044
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and safety of salbutamol sulfate by atomized inhalation in the treatment of pe-diatric asthmatic disease. METHODS:156 children with asthmatic disease were randomly divided into control group (78 cases) and observation group (78 cases). Control group was given oxygen inhalation, anti-infection, relieving cough and reducing phlegm,aminophylline and other conventional treatment;observation group was additionally given 0.03 ml/kg salbutamol sulfate, adding into 2 ml 0.9% Sodium chloride injection,putting into mask atomizer for nebulization,5-10 min every time,twice a day. They were treated for 5 d. Clinical efficacy,asthma remission time,pulmonary rales disappearing time,average hospitalization days and incidence of adverse reactions in 2 groups were observed. RESULTS:The total effective rate in observation group was sig-nificantly higher than control group,asthma remission time,pulmonary rales disappearing time and average hospitalization days were significantly shorter than control group,the differences were statistically significant(P<0.05). There were obvious adverse re-actions in 2 groups during treatment. CONCLUSIONS:Based on conventional treatment,salbutamol sulfate by atomized inhalation has obvious efficacy in the treatment of pediatric asthmatic disease,with good safety.
