Study advances on the roles of apoptosis in hepatocellular carcinoma therapy
10.11904/j.issn.1002-3070.2016.05.013
- VernacularTitle:细胞凋亡在原发性肝癌治疗中的作用研究进展
- Author:
Xiangxuan ZHAO
;
Feng WEN
;
Xiaonan MAO
;
Zaiming LU
- Publication Type:Journal Article
- Keywords:
Apoptosis;
HCC;
Signal pathway;
Target therapy
- From:Practical Oncology Journal
2016;30(5):448-452
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma ( HCC ) is one of the commonest malignant tumors in China .The therapeutic effects of conventional therapies including surgery resection at early stage ,chemotherapy or radiothera-py are greatly less than expected .One of the most possible reasons is the blockage of apoptosis in HCC cells .This review collects literatures about the studies on the roles of key signal pathways including RA ,STAT3,PDT,p53,β-catenin,TRAIL,microRNA and RAS in HCC therapy .This study may contribute greatly to providing outline in-sights for using apoptosis induction in liver cancer therapy .We hope it can promote the development liver cancer therapy in China .
