Analysis of the Utilization of Hepato-protective Drugs in a Third Grade Class A Hospital from 2011 to 2014
10.6039/j.issn.1001-0408.2016.05.06
- VernacularTitle:"某""三甲""医院2011-2014年护肝药物使用分析"
- Author:
Ying ZHU
;
Qianqian YE
;
Ping WANG
;
Min YAN
;
Tao YIN
- Publication Type:Journal Article
- Keywords:
Hepatoprotective drug;
Rational drug use;
DUI;
DDDs;
DDC
- From:
China Pharmacy
2016;27(5):594-597
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To learn the application and tendency of hepatoprotective drugs in a third grade class A hospital dur-ing 2011-2014,and to provide reference for rational drug use. METHODS:DDDs analysis and consumption ordering method were adopted to analyze the change of DDDs,DDC and other index of hepatoprotective drugs in this hospital from 2011 to 2014. RE-SULTS:2011-2014,the amount and DDDs of Hepatoprotective injection in this hospital increased year by year,while oral dosage form decreased year by year. DDC order of each drug kept stable during 2011-2014;DDC and DDDs of drugs for promoting ener-gy metabolism were all in high level,and ornithine aspartate and ademetionine always took up the first 2 places in 4 years. Polyene phosphatidylcholine and Reduced glutathione injection were cheap,but had higher DDDs. Except Glutathione tablet,DUI of other hepatoprotective drugs had no great difference in 3 years,and fluctuated in 2014;hepatoprotective drugs with DUI>1 and DUI<1 occupied a large proportion. From 2010 to 2014,compared with previous year,the drugs with consumption sum/DDDs ratio num-ber close to 1 reduced significantly in the next year,decreasing year by year. CONCLUSIONS:In this hospital,injections are used too frequently,and overuse of drugs for promoting energy metabolism exist. Polyene phosphatidylcholine and Reduced glutathione injection can be used as a valuable drug in the clinic,and their cost are more acceptable,but not in excess.
