Roles of Epstein-Barr virus in the pathogenesis of primary Sj?gren′s syndrome
10.3760/cma.j.issn.0254-5101.2016.09.014
- VernacularTitle:EB病毒在原发性干燥综合征发病机制中的研究进展
- Author:
Yuzhu HE
;
Yikai YU
;
Shaoxian HU
- Publication Type:Journal Article
- Keywords:
Sj?gren′s syndrome;
Epstein-Barr virus;
Interferon;
Lymphoma
- From:
Chinese Journal of Microbiology and Immunology
2016;36(9):712-715
- CountryChina
- Language:Chinese
-
Abstract:
Primary Sj?gren′s syndrome ( pSS) is a kind of chronic autoimmune disease affecting many organs of the body. The pathogenesis of pSS is still debated. Epstein-Barr virus(EBV), also called human herpesvirus-4, belongs to the herpesviridae family. Researchers have found that EBV is associated with pSS. With the deepening of researches, more evidences and opinions about the participation of EBV in the pathogenesis of pSS have emerged. EBV can cause the development of pSS in multiple ways. In this re-view, we summarize the roles of EBV in the pathogenesis of pSS.