Research on the relationship between miRNAs and peritoneal fibrosis
10.11958/20160541
- VernacularTitle:miRNAs与腹膜纤维化关系的研究进展
- Author:
Dong LI
;
Tiekun YAN
- Publication Type:Journal Article
- Keywords:
microRNAs;
retroperitoneal fibrosis;
stromal cells;
peritoneal dialysis;
review;
epithelial mesenchymal transdifferentiation
- From:
Tianjin Medical Journal
2016;44(10):1287-1290
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, microRNAs (miRNAs) have been found to be one of the key factors of post transcriptional gene regulation, which are involved in occurrence and development of many diseases. Peritoneal dialysis (PD) has become an effective alternative treatment approaches for patients with end stage renal disease (ESRD). Peritoneal fibrosis is one of the most important factors leading patients to withdraw from long-term PD, hence restricts the application and development of PD. MicroRNAs are closely related to the development of peritoneal fibrosis. This article reviews the role of miRNAs in the pathogenesis and treatment of peritoneal fibrosis.
